Pedigreed dogs are particularly vulnerable to genetic diseases and as a result of this some breeds are unable to be registered with a large number of national kennel clubs. Different breeds of dogs inherit genetic problems relating to their specific breed. Some of the common genetic defects are hip dysplasia which most often occurs in the larger breed of dogs.
A disease which affects blood platelets known as Willebrand disease is known to be prevalent in Doberman Pinschers. A disease which causes the eyelids of a dog to curl known as entropion occurs in Shar Peis and also other breeds of dogs.
Many pedigreed breeds of dogs have a genetic disorder known as progressive retinal atrophy which affects their eyesight and as they age gets progressively worse. Epilepsy and deafness are inherited disorders which often occur in St Bernard, German Shepherds and Cocker Spaniels.
A serious genetic heart related problem occurs in Golden Retrievers and some other large breeds such as the Newfoundland Dog which disrupts the flow of blood from the heart to the Aorta and could result in cardiac arrest and the death of the dog.
Pedigreed Collie dogs can inherit a genetic disease which prevents their nervous system from functioning and developing properly. If two of these dogs with the same inherited disorder were mated, any puppies which were born would almost certainly, if they survived, have damage to their organs and nervous systems.